New GFCF Study
Nice use of a challenge based methodology
Solid, double blind methodology
Smart controls over history and maturation threats
22 participants is a respectable number, but it still could have been higher.
Can’t answer for the diet’s efficacy for children with actual bowel conditions (Celiac etc)
The autism community has been waiting a long time for a study like this. The best we have seen up till now has been the Elder (2006) study. The methodology is simply rock solid.
I do not predict that this study will have any effect on the advocates of the GF/CF diet. For some reason the GF/CF advocates have been more polite than some of their colleagues. They have typically responded to negative GF/CF studies by trying to find flaws in the study methodology, rather than silly accusations about “shills”.
They will do the same here, I think. My guess is that they will target the number of participants (which is silly in this case). They will also target the time-span (18 weeks) the children were on the GF/CF study in total and on the diet before the first gluten/casein snack was given (4 weeks). Such criticism will be irrelevant however, as there are no standards in this regard. I expect plenty of goal posts to be shifted. I am convinced at this point that being an academic GF/CF advocate means never having to pick an actual study length.